Alleviation of cisplatin‐induced hepatotoxicity by gliclazide: Involvement of oxidative stress and caspase‐3 activity

AIMS: Cisplatin (CP), as an effective alkylating agent, is widely used in cancer treatment, while hepatotoxicity is one of its side effects. Gliclazide (GLZ), as an oral hypoglycemic drug, has antioxidant and anti‐inflammatory properties. This study was designed to investigate the protective effect...

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Bibliografiske detaljer
Udgivet i:Pharmacol Res Perspect
Main Authors: Taghizadeh, Fatemeh, Hosseinimehr, Seyed Jalal, Zargari, Mehryar, Karimpour Malekshah, Abbasali, Mirzaei, Mansoureh, Talebpour Amiri, Fereshteh
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8130655/
https://ncbi.nlm.nih.gov/pubmed/34003600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.788
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