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Alleviation of cisplatin‐induced hepatotoxicity by gliclazide: Involvement of oxidative stress and caspase‐3 activity

AIMS: Cisplatin (CP), as an effective alkylating agent, is widely used in cancer treatment, while hepatotoxicity is one of its side effects. Gliclazide (GLZ), as an oral hypoglycemic drug, has antioxidant and anti‐inflammatory properties. This study was designed to investigate the protective effect...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Pharmacol Res Perspect
Egile Nagusiak: Taghizadeh, Fatemeh, Hosseinimehr, Seyed Jalal, Zargari, Mehryar, Karimpour Malekshah, Abbasali, Mirzaei, Mansoureh, Talebpour Amiri, Fereshteh
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8130655/
https://ncbi.nlm.nih.gov/pubmed/34003600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.788
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