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Epigenetic Silencing of Immune-Checkpoint Receptors in Bone Marrow- Infiltrating T Cells in Acute Myeloid Leukemia

BACKGROUND: Immune-checkpoint (IC) inhibitors have revolutionized the treatment of multiple solid tumors and defined lymphomas, but they are largely ineffective in acute myeloid leukemia (AML). The reason why especially PD1/PD-L1 blocking agents are not efficacious is not well-understood but it may...

詳細記述

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書誌詳細
出版年:Front Oncol
主要な著者: Radpour, Ramin, Stucki, Miriam, Riether, Carsten, Ochsenbein, Adrian F.
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8130556/
https://ncbi.nlm.nih.gov/pubmed/34017684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.663406
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