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Cytotoxic T cells induce proliferation of chronic myeloid leukemia stem cells by secreting interferon-γ

Chronic myeloid leukemia (CML) is a clonal myeloproliferative neoplasia arising from the oncogenic break point cluster region/Abelson murine leukemia viral oncogene homolog 1 translocation in hematopoietic stem cells (HSCs), resulting in a leukemia stem cell (LSC). Curing CML depends on the eradicat...

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Detalhes bibliográficos
Main Authors: Schürch, Christian, Riether, Carsten, Amrein, Michael A., Ochsenbein, Adrian F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3600910/
https://ncbi.nlm.nih.gov/pubmed/23401488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20121229
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