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Selective MAP1LC3C (LC3C) autophagy requires noncanonical regulators and the C-terminal peptide
LC3s are canonical proteins necessary for the formation of autophagosomes. We have previously established that two paralogs, LC3B and LC3C, have opposite activities in renal cancer, with LC3B playing an oncogenic role and LC3C a tumor-suppressing role. LC3C is an evolutionary late gene present only...
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| Udgivet i: | J Cell Biol |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Rockefeller University Press
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8129795/ https://ncbi.nlm.nih.gov/pubmed/33988680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202004182 |
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