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Alzheimer mutant speeds APP transport
APP(S198P) segregates with rare familial forms of Alzheimer’s disease and resides within exon 5, unlike 27 other mutations that reside in exons 16 or 17. In this issue, Zhang et al. (2021. J. Exp. Med. https://doi.org/10.1084/jem.20210313) show that the brains of APP(S198P) transgenic mice accumulat...
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| Published in: | J Exp Med |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Rockefeller University Press
2021
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8129791/ https://ncbi.nlm.nih.gov/pubmed/33988687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20210511 |
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