Nalaganje...
Physiologically‐based pharmacokinetic modeling to predict drug interactions of lemborexant with CYP3A inhibitors
Lemborexant, a recently approved dual orexin receptor antagonist for treatment of adults with insomnia, is eliminated primarily by cytochrome P450 (CYP)3A metabolism. The recommended dose of lemborexant is 5 mg once per night, with a maximum recommended dose of 10 mg once daily. A physiologically‐ba...
Shranjeno v:
| izdano v: | CPT Pharmacometrics Syst Pharmacol |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley and Sons Inc.
2021
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8129715/ https://ncbi.nlm.nih.gov/pubmed/33704920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12606 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|