The nuclear receptor HNF4 drives a brush border gene program conserved across murine intestine, kidney, and embryonic yolk sac

The brush border is comprised of microvilli surface protrusions on the apical surface of epithelia. This specialized structure greatly increases absorptive surface area and plays crucial roles in human health. However, transcriptional regulatory networks controlling brush border genes are not fully...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Chen, Lei, Luo, Shirley, Dupre, Abigail, Vasoya, Roshan P., Parthasarathy, Aditya, Aita, Rohit, Malhotra, Raj, Hur, Joseph, Toke, Natalie H., Chiles, Eric, Yang, Min, Cao, Weihuan, Flores, Juan, Ellison, Christopher E., Gao, Nan, Sahota, Amrik, Su, Xiaoyang, Bonder, Edward M., Verzi, Michael P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8129143/
https://ncbi.nlm.nih.gov/pubmed/34001900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22761-5
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