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DA-DRD5 signaling controls colitis by regulating colonic M1/M2 macrophage polarization

The decrease of neurotransmitter dopamine (DA) levels in the intestine is closely related to the development of inflammatory bowel disease (IBD). However, the functional relevance and underlying mechanistic basis of the effects of DA signaling on IBD remains unclear. Here, we observed that the DRD5...

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Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Liu, Lu, Wu, Yuqing, Wang, Bingwei, Jiang, Yuying, Lin, Lin, Li, Xiaoxi, Yang, Shuo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8129081/
https://ncbi.nlm.nih.gov/pubmed/34001860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03778-6
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