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Colon Macrophages Polarized by Commensal Bacteria Cause Colitis and Cancer through the Bystander Effect

Intestinal commensal bacteria have recently been shown to trigger macrophages to produce diffusible clastogens (or chromosome-breaking factors) through a bystander effect (BSE) that mediates DNA damage and induces chromosomal instability in neighboring cells. Colon macrophages appear central to colo...

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Main Authors: Yang, Yonghong, Wang, Xingmin, Huycke, Thomas, Moore, Danny R, Lightfoot, Stanley A, Huycke, Mark M
Formato: Artigo
Idioma:Inglês
Publicado: Neoplasia Press Inc. 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799201/
https://ncbi.nlm.nih.gov/pubmed/24151540
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