DA-DRD5 signaling controls colitis by regulating colonic M1/M2 macrophage polarization

The decrease of neurotransmitter dopamine (DA) levels in the intestine is closely related to the development of inflammatory bowel disease (IBD). However, the functional relevance and underlying mechanistic basis of the effects of DA signaling on IBD remains unclear. Here, we observed that the DRD5...

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Udgivet i:Cell Death Dis
Main Authors: Liu, Lu, Wu, Yuqing, Wang, Bingwei, Jiang, Yuying, Lin, Lin, Li, Xiaoxi, Yang, Shuo
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8129081/
https://ncbi.nlm.nih.gov/pubmed/34001860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03778-6
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