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Targeted Inhibition of FTO Demethylase Protects Mice Against LPS-Induced Septic Shock by Suppressing NLRP3 Inflammasome
Sepsis refers to the systemic inflammatory response syndrome caused by infection. It is a major clinical problem and cause of death for patients in intensive care units worldwide. The Fat mass and obesity-related protein (FTO) is the primary N (6)-methyladenosine demethylase. However, the role of FT...
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| Publicado no: | Front Immunol |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8128997/ https://ncbi.nlm.nih.gov/pubmed/34017338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.663295 |
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