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Bayesian modeling of skewed X inactivation in genetically diverse mice identifies a novel Xce allele associated with copy number changes

Female mammals are functional mosaics of their parental X-linked gene expression due to X chromosome inactivation (XCI). This process inactivates one copy of the X chromosome in each cell during embryogenesis and that state is maintained clonally through mitosis. In mice, the choice of which parenta...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Genetics
Main Authors: Sun, Kathie Y, Oreper, Daniel, Schoenrock, Sarah A, McMullan, Rachel, Giusti-Rodríguez, Paola, Zhabotynsky, Vasyl, Miller, Darla R, Tarantino, Lisa M, Pardo-Manuel de Villena, Fernando, Valdar, William
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2021
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC8128399/
https://ncbi.nlm.nih.gov/pubmed/33693696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/genetics/iyab034
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