Bayesian modeling of skewed X inactivation in genetically diverse mice identifies a novel Xce allele associated with copy number changes

Female mammals are functional mosaics of their parental X-linked gene expression due to X chromosome inactivation (XCI). This process inactivates one copy of the X chromosome in each cell during embryogenesis and that state is maintained clonally through mitosis. In mice, the choice of which parenta...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Sun, Kathie Y, Oreper, Daniel, Schoenrock, Sarah A, McMullan, Rachel, Giusti-Rodríguez, Paola, Zhabotynsky, Vasyl, Miller, Darla R, Tarantino, Lisa M, Pardo-Manuel de Villena, Fernando, Valdar, William
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8128399/
https://ncbi.nlm.nih.gov/pubmed/33693696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/genetics/iyab034
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