Genetic Architecture of Skewed X Inactivation in the Laboratory Mouse

X chromosome inactivation (XCI) is the mammalian mechanism of dosage compensation that balances X-linked gene expression between the sexes. Early during female development, each cell of the embryo proper independently inactivates one of its two parental X-chromosomes. In mice, the choice of which X...

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Detalhes bibliográficos
Main Authors: Calaway, John D., Lenarcic, Alan B., Didion, John P., Wang, Jeremy R., Searle, Jeremy B., McMillan, Leonard, Valdar, William, Pardo-Manuel de Villena, Fernando
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789830/
https://ncbi.nlm.nih.gov/pubmed/24098153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003853
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