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Copy Number Changes on the X Chromosome in Women with and without Highly Skewed X-Chromosome Inactivation

AIM: To test the hypothesis that microdeletions or microduplications below the resolution of a standard karyotype may be a significant cause of highly skewed X-inactivation (HSXI) in women without a cytogenetically detected X-chromosome anomaly. METHODS: Cases were women with HSXI, defined as ≥85% o...

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Detalles Bibliográficos
Publicado en:Cytogenet Genome Res
Main Authors: Jobanputra, V., Levy, B., Kinney, A., Brown, S., Shirazi, M., Yu, C., Kline, J., Warburton, D.
Formato: Artigo
Idioma:Inglês
Publicado: S. Karger AG 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4315938/
https://ncbi.nlm.nih.gov/pubmed/22516899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000337920
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