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Skewed X Chromosome Inactivation and Trisomic Spontaneous Abortion: No Association

Several studies suggest that highly skewed X chromosome inactivation (HSXI) is associated with recurrent spontaneous abortion. We hypothesized that this association reflects an increased rate of trisomic conceptions due to anomalies on the X chromosome that lead both to HSXI and to a diminished oocy...

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Bibliografiske detaljer
Main Authors: Warburton, Dorothy, Kline, Jennie, Kinney, Ann, Yu, Chih-yu, Levin, Bruce, Brown, Stephen
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2725233/
https://ncbi.nlm.nih.gov/pubmed/19646676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2009.07.002
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