Circulating tumor DNA dynamics and recurrence risk in patients undergoing curative intent resection of colorectal cancer liver metastases: A prospective cohort study

BACKGROUND: In patients with resectable colorectal liver metastases (CRLM), the role of pre- and postoperative systemic therapy continues to be debated. Previous studies have shown that circulating tumor DNA (ctDNA) analysis, as a marker of minimal residual disease, is a powerful prognostic factor i...

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محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:PLoS Med
المؤلفون الرئيسيون: Tie, Jeanne, Wang, Yuxuan, Cohen, Joshua, Li, Lu, Hong, Wei, Christie, Michael, Wong, Hui Li, Kosmider, Suzanne, Wong, Rachel, Thomson, Benjamin, Choi, Julian, Fox, Adrian, Field, Kathryn, Burge, Matthew, Shannon, Jenny, Kotasek, Dusan, Tebbutt, Niall C., Karapetis, Christos, Underhill, Craig, Haydon, Andrew, Schaeffer, Joy, Ptak, Janine, Tomasetti, Cristian, Papadopoulos, Nicholas, Kinzler, Kenneth W., Vogelstein, Bert, Gibbs, Peter
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2021
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC8128260/
https://ncbi.nlm.nih.gov/pubmed/33939694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1003620
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