Serial circulating tumour DNA analysis during multimodality treatment of locally advanced rectal cancer: a prospective biomarker study

OBJECTIVE: For patients with locally advanced rectal cancer (LARC), adjuvant chemotherapy selection following surgery remains a major clinical dilemma. Here we investigated the ability of circulating tumour DNA (ctDNA) to improve risk stratification in patients with LARC. DESIGN: We enrolled patient...

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Bibliografische gegevens
Gepubliceerd in:Gut
Hoofdauteurs: Tie, Jeanne, Cohen, Joshua D, Wang, Yuxuan, Li, Lu, Christie, Michael, Simons, Koen, Elsaleh, Hany, Kosmider, Suzanne, Wong, Rachel, Yip, Desmond, Lee, Margaret, Tran, Ben, Rangiah, David, Burge, Matthew, Goldstein, David, Singh, Madhu, Skinner, lain, Faragher, Ian, Croxford, Matthew, Bampton, Carolyn, Haydon, Andrew, Jones, Ian T, Karapetis, Christos S, Price, Timothy, Schaefer, Mary J, Ptak, Jeanne, Dobbyn, Lisa, Silliman, Natallie, Kinde, Isaac, Tomasetti, Cristian, Papadopoulos, Nickolas, Kinzler, Kenneth, Volgestein, Bert, Gibbs, Peter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265124/
https://ncbi.nlm.nih.gov/pubmed/29420226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2017-315852
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