Serial circulating tumour DNA analysis during multimodality treatment of locally advanced rectal cancer: a prospective biomarker study

OBJECTIVE: For patients with locally advanced rectal cancer (LARC), adjuvant chemotherapy selection following surgery remains a major clinical dilemma. Here we investigated the ability of circulating tumour DNA (ctDNA) to improve risk stratification in patients with LARC. DESIGN: We enrolled patient...

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Bibliografiske detaljer
Udgivet i:Gut
Main Authors: Tie, Jeanne, Cohen, Joshua D, Wang, Yuxuan, Li, Lu, Christie, Michael, Simons, Koen, Elsaleh, Hany, Kosmider, Suzanne, Wong, Rachel, Yip, Desmond, Lee, Margaret, Tran, Ben, Rangiah, David, Burge, Matthew, Goldstein, David, Singh, Madhu, Skinner, lain, Faragher, Ian, Croxford, Matthew, Bampton, Carolyn, Haydon, Andrew, Jones, Ian T, Karapetis, Christos S, Price, Timothy, Schaefer, Mary J, Ptak, Jeanne, Dobbyn, Lisa, Silliman, Natallie, Kinde, Isaac, Tomasetti, Cristian, Papadopoulos, Nickolas, Kinzler, Kenneth, Volgestein, Bert, Gibbs, Peter
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6265124/
https://ncbi.nlm.nih.gov/pubmed/29420226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2017-315852
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