Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer

Detection of circulating tumor DNA (ctDNA) after resection of stage II colon cancer may identify patients at the highest risk of recurrence and help inform adjuvant treatment decisions. We used massively parallel sequencing–based assays to evaluate the ability of ctDNA to detect minimal residual dis...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Sci Transl Med
Main Authors: Tie, Jeanne, Wang, Yuxuan, Tomasetti, Cristian, Li, Lu, Springer, Simeon, Kinde, Isaac, Silliman, Natalie, Tacey, Mark, Wong, Hui-Li, Christie, Michael, Kosmider, Suzanne, Skinner, Iain, Wong, Rachel, Steel, Malcolm, Tran, Ben, Desai, Jayesh, Jones, Ian, Haydon, Andrew, Hayes, Theresa, Price, Tim J., Strausberg, Robert L., Diaz, Luis A., Papadopoulos, Nickolas, Kinzler, Kenneth W., Vogelstein, Bert, Gibbs, Peter
פורמט: Artigo
שפה:Inglês
יצא לאור: 2016
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346159/
https://ncbi.nlm.nih.gov/pubmed/27384348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaf6219
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