Circulating tumor DNA analysis detects minimal residual disease and predicts recurrence in patients with stage II colon cancer

Detection of circulating tumor DNA (ctDNA) after resection of stage II colon cancer may identify patients at the highest risk of recurrence and help inform adjuvant treatment decisions. We used massively parallel sequencing–based assays to evaluate the ability of ctDNA to detect minimal residual dis...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Transl Med
Päätekijät: Tie, Jeanne, Wang, Yuxuan, Tomasetti, Cristian, Li, Lu, Springer, Simeon, Kinde, Isaac, Silliman, Natalie, Tacey, Mark, Wong, Hui-Li, Christie, Michael, Kosmider, Suzanne, Skinner, Iain, Wong, Rachel, Steel, Malcolm, Tran, Ben, Desai, Jayesh, Jones, Ian, Haydon, Andrew, Hayes, Theresa, Price, Tim J., Strausberg, Robert L., Diaz, Luis A., Papadopoulos, Nickolas, Kinzler, Kenneth W., Vogelstein, Bert, Gibbs, Peter
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346159/
https://ncbi.nlm.nih.gov/pubmed/27384348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaf6219
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