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Revealing Functional Insights into ER Proteostasis through Proteomics and Interactomics

The endoplasmic reticulum (ER), responsible for processing approximately one-third of the human proteome including most secreted and membrane proteins, plays a pivotal role in protein homeostasis (proteostasis). Dysregulation of ER proteostasis has been implicated in a number of disease states. As s...

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Détails bibliographiques
Publié dans:Exp Cell Res
Auteurs principaux: Wright, Madison T., Plate, Lars
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8128161/
https://ncbi.nlm.nih.gov/pubmed/33301765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2020.112417
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