Association of Fusobacterium nucleatum with Specific T Cell Subsets in the Colorectal Carcinoma Microenvironment

PURPOSE: While evidence indicates that Fusobacterium nucleatum may promote colorectal carcinogenesis through its suppressive effect on T-cell-mediated antitumor immunity, the specific T-cell subsets involved remain uncertain. EXPERIMENTAL DESIGN: We measured F. nucleatum DNA within tumor tissue by q...

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Publicado no:Clin Cancer Res
Main Authors: Borowsky, Jennifer, Haruki, Koichiro, Lau, Mai Chan, Costa, Andressa Dias, Väyrynen, Juha P., Ugai, Tomotaka, Arima, Kota, da Silva, Annacarolina, Felt, Kristen D., Zhao, Melissa, Gurjao, Carino, Twombly, Tyler S., Fujiyoshi, Kenji, Väyrynen, Sara A., Hamada, Tsuyoshi, Mima, Kosuke, Bullman, Susan, Harrison, Tabitha A., Phipps, Amanda I., Peters, Ulrike, Ng, Kimmie, Meyerhardt, Jeffrey A., Song, Mingyang, Giovannucci, Edward L., Wu, Kana, Zhang, Xuehong, Freeman, Gordon J., Huttenhower, Curtis, Garrett, Wendy S., Chan, Andrew T., Leggett, Barbara A., Whitehall, Vicki L. J., Walker, Neal, Brown, Ian, Bettington, Mark, Nishihara, Reiko, Fuchs, Charles S., Lennerz, Jochen K., Giannakis, Marios, Nowak, Jonathan A., Ogino, Shuji
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8127352/
https://ncbi.nlm.nih.gov/pubmed/33632927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-4009
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