ORMDL3 regulates poly I:C induced inflammatory responses in airway epithelial cells

BACKGROUND: Oroscomucoid 3 (ORMDL3) has been linked to susceptibility of childhood asthma and respiratory viral infection. Polyinosinic-polycytidylic acid (poly I:C) is a synthetic analog of viral double-stranded RNA, a toll-like receptor 3 (TLR3) ligand and mimic of viral infection. METHODS: To inv...

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Détails bibliographiques
Publié dans:BMC Pulm Med
Auteurs principaux: Laura, Gemma, Liu, Yi, Fernandes, Kieran, Willis-Owen, Saffron A. G., Ito, Kazuhiro, Cookson, William O., Moffatt, Miriam F., Zhang, Youming
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2021
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8127224/
https://ncbi.nlm.nih.gov/pubmed/34001091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12890-021-01496-5
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