Macrophage mediated recognition and clearance of Borrelia burgdorferi elicits MyD88-dependent and -independent phagosomal signals that contribute to phagocytosis and inflammation

BACKGROUND: Macrophages play prominent roles in bacteria recognition and clearance, including Borrelia burgdorferi (Bb), the Lyme disease spirochete. To elucidate mechanisms by which MyD88/TLR signaling enhances clearance of Bb by macrophages, we studied wildtype (WT) and MyD88(−/−) Bb-stimulated bo...

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Vydáno v:BMC Immunol
Hlavní autoři: Benjamin, Sarah J., Hawley, Kelly L., Vera-Licona, Paola, La Vake, Carson J., Cervantes, Jorge L., Ruan, Yijun, Radolf, Justin D., Salazar, Juan C.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8127205/
https://ncbi.nlm.nih.gov/pubmed/34000990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-021-00418-8
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