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TRIM37 prevents formation of condensate-organized ectopic spindle poles to ensure mitotic fidelity

Centrosomes are composed of a centriolar core surrounded by pericentriolar material that nucleates microtubules. The ubiquitin ligase TRIM37 localizes to centrosomes, but its centrosomal roles are not yet defined. We show that TRIM37 does not control centriole duplication, structure, or the ability...

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Bibliografske podrobnosti
izdano v:J Cell Biol
Main Authors: Meitinger, Franz, Kong, Dong, Ohta, Midori, Desai, Arshad, Oegema, Karen, Loncarek, Jadranka
Format: Artigo
Jezik:Inglês
Izdano: Rockefeller University Press 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8127006/
https://ncbi.nlm.nih.gov/pubmed/33983387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202010180
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