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Proteostatic imbalance and protein spreading in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder whose exact causative mechanisms are still under intense investigation. Several lines of evidence suggest that the anatomical and temporal propagation of pathological protein species along the neural axis could be among the ma...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Cicardi, Maria Elena, Marrone, Lara, Azzouz, Mimoun, Trotti, Davide
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126909/
https://ncbi.nlm.nih.gov/pubmed/33792056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020106389
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