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Glutamate Transporters and the Excitotoxic Path to Motor Neuron Degeneration in Amyotrophic Lateral Sclerosis

Responsible for the majority of excitatory activity in the central nervous system (CNS), glutamate interacts with a range of specific receptor and transporter systems to establish a functional synapse. Excessive stimulation of glutamate receptors causes excitotoxicity, a phenomenon implicated in bot...

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Detalhes bibliográficos
Main Authors: Foran, Emily, Trotti, Davide
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842587/
https://ncbi.nlm.nih.gov/pubmed/19413484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2009.2444
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