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Breast Cancer Adjuvant Radiotherapy in BRCA1/2, TP53, ATM Genes Mutations: Are There Solved Issues?

BRCA1, BRCA2, TP53 and ATM gene mutations are the most studied tumour suppressor genes (TSGs) influencing the loco-regional approach to breast cancer (BC). Due to altered radio sensitivity of mutated cancer cells, mastectomy has always been advised in most patients with BC linked to TSGs mutations i...

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Dettagli Bibliografici
Pubblicato in:Breast Cancer (Dove Med Press)
Autori principali: Lazzari, Grazia, Buono, Giuseppe, Zannino, Benedetto, Silvano, Giovanni
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove 2021
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126701/
https://ncbi.nlm.nih.gov/pubmed/34012291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/BCTT.S306075
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