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brca2 and tp53 Collaborate in Tumorigenesis in Zebrafish
Germline mutations in the tumor suppressor genes BRCA2 and TP53 significantly influence human cancer risk, and cancers from humans who inherit one mutant allele for BRCA2 or TP53 often display loss of the wildtype allele. In addition, BRCA2-associated cancers often exhibit mutations in TP53. To dete...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3906131/ https://ncbi.nlm.nih.gov/pubmed/24489863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087177 |
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