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brca2 in zebrafish ovarian development, spermatogenesis, and tumorigenesis

Humans with inherited mutations in BRCA2 are at increased risk for developing breast and ovarian cancer; however, the relationship between BRCA2 mutation and these cancers is not understood. Studies of Brca2 mutation by gene targeting in mice are limited, given that homozygous Brca2 mutation typical...

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Detalhes bibliográficos
Main Authors: Shive, Heather R., West, Robert R., Embree, Lisa J., Azuma, Mizuki, Sood, Raman, Liu, Paul, Hickstein, Dennis D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984219/
https://ncbi.nlm.nih.gov/pubmed/20974951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011630107
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