brca2 in zebrafish ovarian development, spermatogenesis, and tumorigenesis

Humans with inherited mutations in BRCA2 are at increased risk for developing breast and ovarian cancer; however, the relationship between BRCA2 mutation and these cancers is not understood. Studies of Brca2 mutation by gene targeting in mice are limited, given that homozygous Brca2 mutation typical...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Shive, Heather R., West, Robert R., Embree, Lisa J., Azuma, Mizuki, Sood, Raman, Liu, Paul, Hickstein, Dennis D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2010
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2984219/
https://ncbi.nlm.nih.gov/pubmed/20974951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011630107
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