Metformin Increases Sarcolemma Integrity and Ameliorates Neuromuscular Deficits in a Murine Model of Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is a genetic neuromuscular disease characterized by progressive muscle weakness and wasting. Stimulation of AMP-activated protein kinase (AMPK) has been demonstrated to increase muscle function and protect muscle against damage in dystrophic mice. Metformin is a wid...

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Dettagli Bibliografici
Pubblicato in:Front Physiol
Autori principali: Dong, Xia, Hui, Tiankun, Chen, Jie, Yu, Zheng, Ren, Dongyan, Zou, Suqi, Wang, Shunqi, Fei, Erkang, Jiao, Huifeng, Lai, Xinsheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Physiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126699/
https://ncbi.nlm.nih.gov/pubmed/34012406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.642908
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