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Impact of uORFs in mediating regulation of translation in stress conditions
BACKGROUND: A large fraction of genes contains upstream ORFs (uORFs) in the 5′ untranslated region (5’UTR). The translation of uORFs can inhibit the translation of the main coding sequence, for example by causing premature dissociation of the two ribosomal units or ribosome stalling. However, it is...
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| Publicado no: | BMC Mol Cell Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8126119/ https://ncbi.nlm.nih.gov/pubmed/33992089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-021-00363-9 |
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