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Impacts of uORF codon identity and position on translation regulation

Translation regulation plays an important role in eukaryotic gene expression. Upstream open reading frames (uORFs) are potent regulatory elements located in 5′ mRNA transcript leaders. Translation of uORFs usually inhibit the translation of downstream main open reading frames, but some enhance expre...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Lin, Yizhu, May, Gemma E, Kready, Hunter, Nazzaro, Lauren, Mao, Mao, Spealman, Pieter, Creeger, Yehuda, McManus, C Joel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755093/
https://ncbi.nlm.nih.gov/pubmed/31392980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz681
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