Impacts of uORF codon identity and position on translation regulation

Translation regulation plays an important role in eukaryotic gene expression. Upstream open reading frames (uORFs) are potent regulatory elements located in 5′ mRNA transcript leaders. Translation of uORFs usually inhibit the translation of downstream main open reading frames, but some enhance expre...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Lin, Yizhu, May, Gemma E, Kready, Hunter, Nazzaro, Lauren, Mao, Mao, Spealman, Pieter, Creeger, Yehuda, McManus, C Joel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
Soggetti:
RNA and RNA-protein complexes
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755093/
https://ncbi.nlm.nih.gov/pubmed/31392980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz681
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