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A Gene Expression Signature to Predict Nucleotide Excision Repair Defects and Novel Therapeutic Approaches

Nucleotide excision repair (NER) resolves DNA adducts, such as those caused by ultraviolet light. Deficient NER (dNER) results in a higher mutation rate that can predispose to cancer development and premature ageing phenotypes. Here, we used isogenic dNER model cell lines to establish a gene express...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Wei, Rongbin, Dai, Hui, Zhang, Jing, Shih, David J. H., Liang, Yulong, Xiao, Pengfeng, McGrail, Daniel J., Lin, Shiaw-Yih
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8125907/
https://ncbi.nlm.nih.gov/pubmed/34066883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22095008
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