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A Gene Expression Signature to Predict Nucleotide Excision Repair Defects and Novel Therapeutic Approaches

Nucleotide excision repair (NER) resolves DNA adducts, such as those caused by ultraviolet light. Deficient NER (dNER) results in a higher mutation rate that can predispose to cancer development and premature ageing phenotypes. Here, we used isogenic dNER model cell lines to establish a gene express...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Wei, Rongbin, Dai, Hui, Zhang, Jing, Shih, David J. H., Liang, Yulong, Xiao, Pengfeng, McGrail, Daniel J., Lin, Shiaw-Yih
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8125907/
https://ncbi.nlm.nih.gov/pubmed/34066883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22095008
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