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Cell Shape and Matrix Stiffness Impact Schwann Cell Plasticity via YAP/TAZ and Rho GTPases

Schwann cells (SCs) are a highly plastic cell type capable of undergoing phenotypic changes following injury or disease. SCs are able to upregulate genes associated with nerve regeneration and ultimately achieve functional recovery. During the regeneration process, the extracellular matrix (ECM) and...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Xu, Zhenyuan, Orkwis, Jacob A., Harris, Greg M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8124465/
https://ncbi.nlm.nih.gov/pubmed/34062912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22094821
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