RNAi screens for Rho GTPase regulators of cell shape and YAP/TAZ localisation in triple negative breast cancer

In order to metastasise, triple negative breast cancer (TNBC) must make dynamic changes in cell shape. The shape of all eukaryotic cells is regulated by Rho Guanine Nucleotide Exchange Factors (RhoGEFs), which activate Rho-family GTPases in response to mechanical and informational cues. In contrast,...

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發表在:Sci Data
Main Authors: Pascual-Vargas, Patricia, Cooper, Samuel, Sero, Julia, Bousgouni, Vicky, Arias-Garcia, Mar, Bakal, Chris
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2017
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Data Descriptor
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5332010/
https://ncbi.nlm.nih.gov/pubmed/28248929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sdata.2017.18
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