Cocrystal of Apixaban–Quercetin: Improving Solubility and Bioavailability of Drug Combination of Two Poorly Soluble Drugs

Drug combinations have been the hotspot of the pharmaceutical industry, but the promising applications are limited by the unmet solubility and low bioavailability. In this work, novel cocrystals, consisting of two antithrombotic drugs with poor solubility and low bioavailability in vivo, namely, api...

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Bibliografske podrobnosti
izdano v:Molecules
Main Authors: Zhang, Li, Kong, Dewen, Wang, Hongjuan, Jiao, Lingtai, Zhao, Xiaoyue, Song, Junke, Yang, Dezhi, Yang, Haiguang, Yang, Shiying, Du, Guanhua, Lu, Yang
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8124247/
https://ncbi.nlm.nih.gov/pubmed/34063645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26092677
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