Cocrystal of Apixaban–Quercetin: Improving Solubility and Bioavailability of Drug Combination of Two Poorly Soluble Drugs

Drug combinations have been the hotspot of the pharmaceutical industry, but the promising applications are limited by the unmet solubility and low bioavailability. In this work, novel cocrystals, consisting of two antithrombotic drugs with poor solubility and low bioavailability in vivo, namely, api...

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Publicado no:Molecules
Main Authors: Zhang, Li, Kong, Dewen, Wang, Hongjuan, Jiao, Lingtai, Zhao, Xiaoyue, Song, Junke, Yang, Dezhi, Yang, Haiguang, Yang, Shiying, Du, Guanhua, Lu, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8124247/
https://ncbi.nlm.nih.gov/pubmed/34063645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26092677
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