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Berberrubine Phosphate: A Selective Fluorescent Probe for Quadruplex DNA

A phosphate-substituted, zwitterionic berberine derivative was synthesized and its binding properties with duplex DNA and G4-DNA were studied using photometric, fluorimetric and polarimetric titrations and thermal DNA denaturation experiments. The ligand binds with high affinity toward both DNA form...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Wickhorst, Peter Jonas, Ihmels, Heiko
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8124163/
https://ncbi.nlm.nih.gov/pubmed/33924894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26092566
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