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Identification of CRYAB(+) KCNN3(+) SOX9(+) Astrocyte-Like and EGFR(+) PDGFRA(+) OLIG1(+) Oligodendrocyte-Like Tumoral Cells in Diffuse IDH1-Mutant Gliomas and Implication of NOTCH1 Signalling in Their Genesis

SIMPLE SUMMARY: Diffuse grade II IDH-mutant gliomas are rare brain tumors mainly affecting young patients. These tumors are composed of different populations of tumoral cells. Little is known of these cells and how they are generated. These different cells may show different sensitivity to treatment...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Augustus, Meera, Pineau, Donovan, Aimond, Franck, Azar, Safa, Lecca, Davide, Scamps, Frédérique, Muxel, Sophie, Darlix, Amélie, Ritchie, William, Gozé, Catherine, Rigau, Valérie, Duffau, Hugues, Hugnot, Jean-Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8123787/
https://ncbi.nlm.nih.gov/pubmed/33925547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13092107
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