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The Effect of a New Glucose–Methotrexate Conjugate on Acute Lymphoblastic Leukemia and Non-Hodgkin’s Lymphoma Cell Lines

Patients with hematologic malignancies require intensive therapies, including high-dose chemotherapy. Antimetabolite–methotrexate (MTX) has been used for many years in the treatment of leukemia and in lymphoma patients. However, the lack of MTX specificity causes a significant risk of morbidity, mor...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Woźniak, Marta, Makuch, Sebastian, Pastuch-Gawołek, Gabriela, Wiśniewski, Jerzy, Szeja, Wiesław, Nowak, Martyna, Krawczyk, Monika, Agrawal, Siddarth
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8123764/
https://ncbi.nlm.nih.gov/pubmed/33925555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26092547
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