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Synthesis and Preliminary Evaluation of Biological Activity of Glycoconjugates Analogues of Acyclic Uridine Derivatives

Herein we present the methodology for obtaining glycosyltransferase inhibitors, analogues of natural enzyme substrates of donor-type: UDP-glucose and UDP-galactose. The synthesis concerned glycoconjugates, nucleoside analogues containing an acyclic ribose mimetic linked to a uracil moiety in their s...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Komor, Roman, Pastuch-Gawolek, Gabriela, Krol, Ewelina, Szeja, Wieslaw
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6222857/
https://ncbi.nlm.nih.gov/pubmed/30104510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23082017
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