Delineating copy number and clonal substructure in human tumors from single-cell transcriptomes

Single-cell transcriptomic analysis is widely used to study human tumors. However it remains challenging to distinguish normal cell types in the tumor microenvironment from malignant cells and to resolve clonal substructure within the tumor. To address these challenges, we developed an integrative B...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Nat Biotechnol
Главные авторы: Gao, Ruli, Bai, Shanshan, Henderson, Ying C., Lin, Yiyun, Schalck, Aislyn, Yan, Yun, Kumar, Tapsi, Hu, Min, Sei, Emi, Davis, Alexander, Wang, Fang, Shaitelman, Simona F., Wang, Jennifer Rui, Chen, Ken, Moulder, Stacy, Lai, Stephen Y., Navin, Nicholas E.
Формат: Artigo
Язык:Inglês
Опубликовано: 2021
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8122019/
https://ncbi.nlm.nih.gov/pubmed/33462507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41587-020-00795-2
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы