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Phenotypic Differences between the Alzheimer’s Disease-Related hAPP-J20 Model and Heterozygous Zbtb20 Knock-Out Mice

Diverse gene products contribute to the pathogenesis of Alzheimer’s disease (AD). Experimental models have helped elucidate their mechanisms and impact on brain functions. Human amyloid precursor protein (hAPP) transgenic mice from line J20 (hAPP-J20 mice) are widely used to simulate key aspects of...

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Bibliografiske detaljer
Udgivet i:eNeuro
Main Authors: Gulbranson, Daniel R., Ho, Kaitlyn, Yu, Gui-Qiu, Yu, Xinxing, Das, Melanie, Shao, Eric, Kim, Daniel, Zhang, Weiping J., Choudhary, Krishna, Thomas, Reuben, Mucke, Lennart
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2021
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8121260/
https://ncbi.nlm.nih.gov/pubmed/33833046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0089-21.2021
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