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Phenotypic Differences between the Alzheimer’s Disease-Related hAPP-J20 Model and Heterozygous Zbtb20 Knock-Out Mice

Diverse gene products contribute to the pathogenesis of Alzheimer’s disease (AD). Experimental models have helped elucidate their mechanisms and impact on brain functions. Human amyloid precursor protein (hAPP) transgenic mice from line J20 (hAPP-J20 mice) are widely used to simulate key aspects of...

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Detalhes bibliográficos
Publicado no:eNeuro
Principais autores: Gulbranson, Daniel R., Ho, Kaitlyn, Yu, Gui-Qiu, Yu, Xinxing, Das, Melanie, Shao, Eric, Kim, Daniel, Zhang, Weiping J., Choudhary, Krishna, Thomas, Reuben, Mucke, Lennart
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8121260/
https://ncbi.nlm.nih.gov/pubmed/33833046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0089-21.2021
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