טוען...

Ablation of Cellular Prion Protein Does Not Ameliorate Abnormal Neural Network Activity or Cognitive Dysfunction in the J20 Line of Human Amyloid Precursor Protein Transgenic Mice

Previous studies suggested that the cellular prion protein (PrP(c)) plays a critical role in the pathogenesis of Alzheimer's disease (AD). Specifically, amyloid-β (Aβ) oligomers were proposed to cause synaptic and cognitive dysfunction by binding to PrP(c). To test this hypothesis, we crossed h...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Cissé, Moustapha, Sanchez, Pascal E., Kim, Daniel H., Ho, Kaitlyn, Yu, Gui-Qiu, Mucke, Lennart
פורמט: Artigo
שפה:Inglês
יצא לאור: Society for Neuroscience 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3314063/
https://ncbi.nlm.nih.gov/pubmed/21775587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1459-11.2011
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!