Use of simulated vaginal and menstrual fluids to model in vivo discolouration of silicone elastomer vaginal rings

Vaginal rings releasing antiretrovirals – either alone or in combination with contraceptive progestins – are being developed for prevention of human immunodeficiency virus (HIV) transmission via vaginal sex. Following Phase I trials, significant discolouration was observed on the surface of investig...

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Detalhes bibliográficos
Publicado no:Int J Pharm X
Main Authors: McCoy, Clare F., Spence, Patrick, Dallal Bashi, Yahya H., Murphy, Diarmaid J., Boyd, Peter, Dangi, Bindi, Derrick, Tiffany, Devlin, Bríd, Kleinbeck, Kyle, Malcolm, R. Karl
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8120934/
https://ncbi.nlm.nih.gov/pubmed/34027386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpx.2021.100081
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