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Modified silicone elastomer vaginal gels for sustained release of antiretroviral HIV microbicides
We previously reported non-aqueous silicone elastomer gels (SEGs) for sustained vaginal administration of the CCR5-targeted entry inhibitor maraviroc. Here, we describe chemically modified SEGs (h-SEGs) in which the hydrophobic cyclomethicone component was partially replaced with relatively hydrophi...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3989844/ https://ncbi.nlm.nih.gov/pubmed/24585370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.23913 |
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